Interim reports

Interim reports for data monitoring committee review vs final reports for regulatory filing

Independent data monitoring committee is responsible for review of the ongoing safety of participants and the validity and integrity of data in clinical trials and for making recommendations to the sponsor whether the trial should continue as planned, be modified or be terminated because of safety concern, futility of the trial, or treatment benefit. Use of DMCs by government and industry spons...

Lessons from the H1N1 influenza pandemic in French overseas territories and interim reports from metropolitan France.

Management of the first wave of the H1N1 influenza pandemic has presented major logistic and infrastructural challenges for public health authorities worldwide. Mangement in the Northern hemisphere has been in part guided by information provided by countries in the Southern hemisphere, which were the first to experience a winter outbreak of the new influenza H1N1 variant virus. Following report...

Synthesis of Jisc Curriculum Delivery Projects Interim Reports Findings: A) Current Findings on How Learners Are Experiencing Innovations in Curriculum Delivery Oxford Centre for Staff and Learning Development Synthesis of Jisc Curriculum Delivery Projects Interim Reports

Aims: To review the March 2010 JISC Transferring Curriculum Delivery Through Technology Interim reports with a view to drawing out a) evidence of the learners’ experiences of curriculum delivery in these projects; b) methods used to gather data on the learners’ experiences described in the reports, and c) evidence of where the Learner Experiences of e-Learning (LEX) programme has made an impact...

NWC interim

Surviving the Interim: Insights Into Interim Survival Analysis

Pre-specified interim analyses may be performed to evaluate whether a clinical trial can be halted prematurely for overwhelming efficacy and/or futility. This approach is somewhat more complex when the primary endpoint is a survival analysis. This paper provides an overview of performing the initial calculations and actual interim analyses using SAS ® PROC SEQDESIGN and PROC SEQTEST, EAST ® sof...